Board Game Arena

Hi everyone.

Still fairly new to this game so looking for tips.

Clearly the doublers J B K are game winners and worth snapping up early if you can. And clearly E and A also are great.

However, what about the next bunch down: if I have a chance on turn 2 say to buy Q X Z or buy O I (or S N R), which do you think is better? This often seems to be a choice I am faced with and I am not sure whether to go with the special ability or the common letter. Thanks!

In turn 2, most of times I pick a special. You can still save cash to buy a big patent later, and specials are hard to come by.