I wrote a long answer but it was deleted. Short version now.
Color black is important since both can score with it, color red is not important since our opponent can only score 1 point.
I would start with 2 black from tile 4 and put it in row 4. Thus I keep flexibility in row 3 which is still open for black or blue.
Our opponent is more-or-less forced to take 3 black + start tile from the middle and he already starts to fill his discard row with 2 tiles.
I would probably take 3 blue from tile 2 for my 2nd move to bring 2 of the reds together in the middle. With this move I want to hinder our opponent to take 1 red each turn. It is better if he fills up his 5th row fast and is forced to take negative points in his many turns to come.
It should be easy to win the game since our opponent will amass negative points with colors black, white, blue while we still have some flexibility via row 5.
[edit: starting with 2 white from tile 4 and putting them in row 3 looks also promising. It puts 5 blacks together (which our opponent is not happy to take while we are willing to do so.]
